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Notice Summary

Title:
UK-London: Provision of Single Cell Western Blot Equipment
Document Ref:
GB003ZM317570
Document Type:
Contract Notice - Other
Published By:
Public Health England
Date Published:
11 December 2019
Deadline Date:
19 December 2019
Document Source:
Framework/DPS:
No
Alert Profile:
Labels:

Notice Abstract

Public Health England (PHE) is seeking to procure single cell western blot equipment its Centre for Radiation, Chemical and Environmental Hazards (CRCE). The equipment will be used to research the processes underpinning radiation-induced cardiovascular disease. The current "safe-level" of exposure to radiation that is permissible, is based solely on radiation doses that can cause cancers. However, it is becoming increasingly clear that cancer may not be the only disease that can be induced by radiation. Cardiovascular disease is at the top of the list of potential non-cancer ailments that can be instigated by radiation. The single cell western blot equipment must meet the following mandatory requirements: - The system must be capable of microscale separations, quantitation, and immunodetection of proteins in single-cells and must be able to analyse around 1000 single cells per run. - The system must be compatible with conventional western primary antibodies and standard fluorescently tagged secondary antibodies for immune-probing. - The instrument must have capability of multiplexing at least 2 target proteins per run and must offer possibility of stripping and reprobing with different set of antibodies. - The analysis software must perform automatic detection of lanes and protein peaks and offer automatic peak quantification. Desirable requirement: - Bench-top footprint would be advantage Industry •Immunoassay analysers - 38434580

Notice Details

CONTRACT NOTICE – NATIONAL

SUPPLIES

1 Authority Details

1.1

Authority Name and Address

Public Health England
N/A
London UK
N/A N/A
anna.gibson@phe.gov.uk N/A

1.2

Address from which documentation may be obtained

As in 1.1

1.3

Completed documents must be returned to:

As in 1.1

2 Contract Details

2.1

Title

Provision of Single Cell Western Blot Equipment

2.2

Description of the goods or services required

Public Health England (PHE) is seeking to procure single cell western blot equipment its Centre for Radiation, Chemical and Environmental Hazards (CRCE).

The equipment will be used to research the processes underpinning radiation-induced cardiovascular disease. The current "safe-level" of exposure to radiation that is permissible, is based solely on radiation doses that can cause cancers. However, it is becoming increasingly clear that cancer may not be the only disease that can be induced by radiation. Cardiovascular disease is at the top of the list of potential non-cancer ailments that can be instigated by radiation.

The single cell western blot equipment must meet the following mandatory requirements:

- The system must be capable of microscale separations, quantitation, and immunodetection of proteins in single-cells and must be able to analyse around 1000 single cells per run.

- The system must be compatible with conventional western primary antibodies and standard fluorescently tagged secondary antibodies for immune-probing.

- The instrument must have capability of multiplexing at least 2 target proteins per run and must offer possibility of stripping and reprobing with different set of antibodies.

- The analysis software must perform automatic detection of lanes and protein peaks and offer automatic peak quantification.

Desirable requirement:

- Bench-top footprint would be advantage

Industry

•Immunoassay analysers - 38434580

2.3

Notice Coding and Classification

2.4

Total quantity or scope of tender

Location of contract South East

Value of contract £20k

Contract start date 20 December 2019

Contract end date 31 December 2020

3 Conditions for Participation

3.1

Minimum standards and qualification required

4 Administrative Information

4.1

Type of Procedure

The procedure type is unknown.

4.2

Reference number attributed to the notice by the contracting authority

n/a

4.3

Time Limits

   19-12-2019  Time 12:00

4.5

Language or languages in which tenders or requests to participate can be drawn up

EN 

4.6

Tender Submission Postbox

5 Other Information

5.1

Additional Information

Please visit the following portal to view this notice:

https://www.contractsfinder.service.gov.uk/Notice/acf8a7e4-6a0d-426a-b455-e5da497b8479?p=@xUlRRPT0=NjJNT08=UFQ

Closing date 19 December 2019

(MT Ref:317570)

5.2

Additional Documentation

5.3

Publication date of this notice

 10-12-2019

Current Notes