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Notice Summary

UK-Southampton: 19/39 Minimally Invasive Operative Interventions for Bladder Outlet Obstruction
GB003ZM291139
National Insttitute for Health Research
27 March 2019
31 July 2019
Contract Notice - Other
No

Notice Abstract

The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research topic: 19/39 Minimally invasive operative interventions for bladder outlet obstruction due to benign prostatic hyperplasia Rationale: Lower urinary tract symptoms due to benign prostatic hyperplasia are a problem for many men as they become older. Operative intervention is only offered when symptoms have not responded to conservative management and drug treatment. Transurethral resection of the prostate has been the most common form of surgery, but in recent years a number of different modalities of treatment have been developed and are available in the NHS. Techniques include laser ablation, enucleation techniques including Holmium Laser Enucleation of the Prostate (HoLEP), prostatic artery embolisation, urethral lift, urethral stents and water jet and water vapour ablation. NICE has released Interventional Procedures guidance on a number of these techniques and given recommendations about their use and the need for further research. Most of the new techniques tend to be less invasive than TURP, have fewer serious side effects and some may be carried out as day case procedures. However research has not yet provided definitive evidence of comparative benefit or cost effectiveness, or whether their use subsequently leads to repeat or more invasive surgery. The purpose of this call is to provide new data on a number of interventions that may be carried out as day case procedures, including transurethral water vapour ablation, and to use indirect comparisons or network meta-analysis to compare multiple interventions. Applicants should be mindful of recent studies such as the GOLIATH study, UK-ROPE and, the HTA UNBLOCS trial and explain how their research would add significantly to knowledge in this field, rather than duplicate recent research.

Notice Details

CONTRACT NOTICE – NATIONAL

SERVICES

1 Authority Details

1.1

Authority Name and Address


National Insttitute for Health Research

N/A

Southampton


UK

N/A

N/A


N/A

1.2

Address from which documentation may be obtained

As in 1.1

1.3

Completed documents must be returned to:

As in 1.1

2 Contract Details

2.1

Title

19/39 Minimally Invasive Operative Interventions for Bladder Outlet Obstruction

2.2

Description of the goods or services required

The Health Technology Assessment Programme is accepting stage 1 applications to their commissioned workstream for this primary research topic:

19/39 Minimally invasive operative interventions for bladder outlet obstruction due to benign prostatic hyperplasia

Rationale:

Lower urinary tract symptoms due to benign prostatic hyperplasia are a problem for many men as they become older. Operative intervention is only offered when symptoms have not responded to conservative management and drug treatment.

Transurethral resection of the prostate has been the most common form of surgery, but in recent years a number of different modalities of treatment have been developed and are available in the NHS. Techniques include laser ablation, enucleation techniques including Holmium Laser Enucleation of the Prostate (HoLEP), prostatic artery embolisation, urethral lift, urethral stents and water jet and water vapour ablation.

NICE has released Interventional Procedures guidance on a number of these techniques and given recommendations about their use and the need for further research. Most of the new techniques tend to be less invasive than TURP, have fewer serious side effects and some may be carried out as day case procedures.

However research has not yet provided definitive evidence of comparative benefit or cost effectiveness, or whether their use subsequently leads to repeat or more invasive surgery.

The purpose of this call is to provide new data on a number of interventions that may be carried out as day case procedures, including transurethral water vapour ablation, and to use indirect comparisons or network meta-analysis to compare multiple interventions.

Applicants should be mindful of recent studies such as the GOLIATH study, UK-ROPE and, the HTA UNBLOCS trial and explain how their research would add significantly to knowledge in this field, rather than duplicate recent research.

2.3

Notice Coding and Classification

2.4

Total quantity or scope of tender

3 Conditions for Participation

3.1

Minimum standards and qualification required

4 Administrative Information

4.1

Type of Procedure

The procedure type is unknown.

4.2

Reference number attributed to the notice by the contracting authority

19/39

4.3

Time Limits

   31-07-2019  Time 13:00

4.5

Language or languages in which tenders or requests to participate can be drawn up

EN 

4.6

Tender Submission Postbox

5 Other Information

5.1

Additional Information

Please visit the following portal to view this notice:

https://www.nihr.ac.uk/funding-and-support/funding-opportunities/1939-minimally-invasive-operative-interventions-for-bladder-outlet-obstruction-due-to-benign-prostatic-hyperplasia/10567

The deadline for applications is 1pm, 31 July 2019.

(MT Ref:291139)

5.2

Additional Documentation

5.3

Publication date of this notice

 27-03-2019