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Notice Summary

Title:
UK-London: Provision of an Exosome and Macrovesicle Quantification and Profiling System
Document Ref:
GB003ZM304224
Document Type:
Contract Notice - Other
Published By:
Public Health England
Date Published:
30 July 2019
Deadline Date:
13 August 2019
Document Source:
Framework/DPS:
No
Alert Profile:
Labels:

Notice Abstract

Public Health England (PHE) requires the provision of an Exosome and Macrovesicle Quantification and Profiling System for use in its Cancer Mechanisms and Biomarkers Group laboratories. The system will be used mainly for elucidating the role of extracellular vesicles in propagating bystander effects and mediating the risk of Acute Myeloid Leukaemia (AML) development in the bone marrow. The proposed solution MUST be able to fulfil all of the following requirements: - Be able to quantify extracellular vesicles on a particle-by-particle basis. - Be able to measure extracellular vesicles ranging from 30 nm to 15 microns in size. - Be able to calculate the concentration of extracellular vesicles within a given size range. - Allow for the study of how certain parameters may affect the size distribution in a heterogenous extracellular vesicle population. - Provide information on specific size subtypes. - Be able to characterize individual particles in a sample population, allowing for multimodal samples to be analysed. - Be able to measure the particles' dry size. - Be able to calculate individual particle zeta potential. - Allow for subpopulation determination (e.g. particle number per ml) associated with a given size range. Industry •Detection and analysis apparatus - 38430000

Notice Details

CONTRACT NOTICE – NATIONAL

SERVICES

1 Authority Details

1.1

Authority Name and Address

Public Health England
N/A
London UK
N/A N/A
kallie.rivers@phe.gov.uk N/A

1.2

Address from which documentation may be obtained

As in 1.1

1.3

Completed documents must be returned to:

As in 1.1

2 Contract Details

2.1

Title

Provision of an Exosome and Macrovesicle Quantification and Profiling System

2.2

Description of the goods or services required

Public Health England (PHE) requires the provision of an Exosome and Macrovesicle Quantification and Profiling System for use in its Cancer Mechanisms and Biomarkers Group laboratories. The system will be used mainly for elucidating the role of extracellular vesicles in propagating bystander effects and mediating the risk of Acute Myeloid Leukaemia (AML) development in the bone marrow.

The proposed solution MUST be able to fulfil all of the following requirements:

- Be able to quantify extracellular vesicles on a particle-by-particle basis.

- Be able to measure extracellular vesicles ranging from 30 nm to 15 microns in size.

- Be able to calculate the concentration of extracellular vesicles within a given size range.

- Allow for the study of how certain parameters may affect the size distribution in a heterogenous extracellular vesicle population.

- Provide information on specific size subtypes.

- Be able to characterize individual particles in a sample population, allowing for multimodal samples to be analysed.

- Be able to measure the particles' dry size.

- Be able to calculate individual particle zeta potential.

- Allow for subpopulation determination (e.g. particle number per ml) associated with a given size range.

Industry

•Detection and analysis apparatus - 38430000

2.3

Notice Coding and Classification

2.4

Total quantity or scope of tender

Location of contract Any region

Value of contract £25k

Contract start date 22 August 2019

Contract end date 21 August 2024

3 Conditions for Participation

3.1

Minimum standards and qualification required

4 Administrative Information

4.1

Type of Procedure

The procedure type is unknown.

4.2

Reference number attributed to the notice by the contracting authority

n/a

4.3

Time Limits

   13-08-2019  Time 12:00

4.5

Language or languages in which tenders or requests to participate can be drawn up

EN 

4.6

Tender Submission Postbox

5 Other Information

5.1

Additional Information

Please visit the following portal to view this notice:

https://www.contractsfinder.service.gov.uk/Notice/19c07416-2bd3-47f6-bee7-1a2b484eb058?p=@FQxblRRPT0=NjJNT08=U

Closing date 13 August 2019

(MT Ref:304224)

5.2

Additional Documentation

5.3

Publication date of this notice

 30-07-2019

Current Notes